Hormonal
Metformin treatment in type 2 diabetes patients significantly reduces the incidence of total, colorectal, liver, and pancreatic cancers, with effects observed at low doses (≤500 mg/day).
If you have Type 2 Diabetes and are taking metformin, this study suggests you may already be benefiting from a reduced risk of several cancers, including colorectal, liver, and pancreatic cancer, even at low doses (≤500 mg/day). Do not stop or change your medication without consulting your doctor, but be aware that your current treatment may offer protective benefits beyond blood sugar control.
Metformin can reduce the incidences of several gastroenterological cancers in treated diabetes... Metformin dosage for a significant decrease in cancer incidence was ≤500 mg/day.
Why this rating
Large prospective cohort (n=480,984) with robust statistical adjustments, though observational design limits causal inference.
Source
Type 2 diabetes increases and metformin reduces total, colorectal, liver and pancreatic cancer incidences in Taiwanese: a representative population prospective cohort study of 800,000 individuals
Meei-Shyuan Lee et al. · BMC Cancer · 2011
DOI 10.1186/1471-2407-11-20
Related findings · Hormonal
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