Research
Adherence
The observed antidepressant effect of resistance exercise training is smaller in trials where allocation and/or assessment was blinded, indicating that unblinded trials may overestimate the effect due to bias.
Be aware that the large effects often cited in unblinded studies may be inflated by participant expectations. However, even in rigorous, blinded trials, resistance exercise training still produces a significant, moderate reduction in depressive symptoms.
GoodQualifiesHIGH confidence
Smaller reductions in depressive symptoms were derived from randomized clinical trials with blinded allocation and/or assessment.
Why this rating
Meta-regression analysis of trial quality.
Source
Association of Efficacy of Resistance Exercise Training With Depressive Symptoms
Brett R. Gordon et al. · JAMA Psychiatry · 2018
Meta-analysis · 33 studiesCited 462×
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