Research
Macro partitioning
Dietary interventions, particularly those involving calorie restriction, high protein, or specific macronutrient compositions, can alter gut microbiota composition, with changes often correlating with weight loss outcomes.
Adopting a calorie-restricted diet combined with increased physical activity can positively shift gut microbiota, particularly increasing beneficial bacteria like Bacteroides fragilis and Lactobacillus. These shifts are more pronounced in individuals who achieve significant weight loss.
GoodSupportsHIGH confidence
The investigation established that bacterial numbers were greatest in individuals on the maintenance diet and that the gram negative Bacteroides and the gram positive C. coccoides were the most abundant bacterial groups... It was apparent that the bifidobacteria, Roseburia spp and E. rectale from the Clostridium group were all negatively impacted upon by decreased carbohydrate intake.
Why this rating
Multiple human and animal studies are cited showing consistent trends in microbiota shifts in response to specific diets.
Source
The gut microbiota and its relationship to diet and obesity
Siobhan F. Clarke et al. · Gut Microbes · 2012
DOI 10.4161/gmic.20168
narrative_reviewCited 460×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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