Research
Hormonal
Intensive glycemic control (targeting HbA1c ≤ 7%) significantly reduces cardiovascular events and microvascular complications in patients with Type 1 Diabetes.
If you have Type 1 Diabetes, keeping your blood sugar as close to normal as possible (targeting an A1c around 7%) is proven to significantly lower your risk of heart disease and kidney/eye damage over the long term.
StrongSupportsHIGH confidence
The DCCT and EDIC trials do suggest that intensive glycemic therapy (goal HbA1c ≥ 7%) can help reduce rates of microvascular and macrovascular disease in T1D.
Why this rating
Based on long-term follow-up of DCCT and EDIC trials.
Source
Diabetes and cardiovascular disease: Epidemiology, biological mechanisms, treatment recommendations and future research
Benjamin M Leon · World Journal of Diabetes · 2015
DOI 10.4239/wjd.v6.i13.1246
narrative_reviewCited 1,237×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
More from this paper
- Intensive glycemic control (targeting HbA1c ≤ 6.5%) does not significantly reduce cardiovascular events or all-cause mortality in patients with Type 2 Diabetes compared to standard control, and may increase mortality risk.Strong
- Statins significantly reduce cardiovascular events, all-cause mortality, and stroke in patients with Type 2 Diabetes, regardless of baseline cholesterol levels.Strong
- Intensive blood pressure control (targeting systolic BP < 120 mmHg) does not reduce fatal or nonfatal major cardiovascular events in patients with Type 2 Diabetes compared to standard control (< 140 mmHg) and increases adverse events.Strong
Related findings · Hormonal
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