Research

Macro partitioning

Current evidence does not clearly support cardiovascular guidelines that encourage high consumption of polyunsaturated fatty acids (omega-3 and omega-6) or low consumption of total saturated fats for coronary risk reduction.

Current evidence does not strongly support the specific guideline advice to drastically increase polyunsaturated fat intake or strictly limit total saturated fat for the purpose of preventing coronary disease. While trans fats should still be avoided, the distinction between saturated and unsaturated fats may be less critical for heart health than previously believed, according to this large meta-analysis.

GoodRefutesHIGH confidence
Current evidence does not clearly support cardiovascular guidelines that encourage high consumption of polyunsaturated fatty acids and low consumption of total saturated fats.
Rajiv Chowdhury et al. · Annals of Internal Medicine · 2014

Why this rating

Large-scale meta-analysis of 32 observational studies and 27 RCTs, though observational studies have inherent bias risks.

Source

Association of Dietary, Circulating, and Supplement Fatty Acids With Coronary Risk

Rajiv Chowdhury et al. · Annals of Internal Medicine · 2014

Meta-analysis · 72 studiesCited 1,144×
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