Macro partitioning
Current evidence does not clearly support cardiovascular guidelines that encourage high consumption of polyunsaturated fatty acids (omega-3 and omega-6) or low consumption of total saturated fats for coronary risk reduction.
Current evidence does not strongly support the specific guideline advice to drastically increase polyunsaturated fat intake or strictly limit total saturated fat for the purpose of preventing coronary disease. While trans fats should still be avoided, the distinction between saturated and unsaturated fats may be less critical for heart health than previously believed, according to this large meta-analysis.
Current evidence does not clearly support cardiovascular guidelines that encourage high consumption of polyunsaturated fatty acids and low consumption of total saturated fats.
Why this rating
Large-scale meta-analysis of 32 observational studies and 27 RCTs, though observational studies have inherent bias risks.
Source
Association of Dietary, Circulating, and Supplement Fatty Acids With Coronary Risk
Rajiv Chowdhury et al. · Annals of Internal Medicine · 2014
DOI 10.7326/m13-1788
More from this paper
- Supplementation with long-chain omega-3 and omega-6 polyunsaturated fatty acids does not statistically significantly reduce the risk of coronary outcomes in randomized controlled trials.Good
- Trans fatty acid intake is positively associated with coronary disease risk, supporting guidelines to avoid them.Good
Related findings · Macro partitioning
- Total daily protein intake of 1.6 g/kg/day is sufficient for maximizing resistance training-induced muscle gains, with an upper confidence interval of 2.2 g/kg/day.Strong
- Resistance exercise training combined with sufficient dietary protein intake acts synergistically to maximize skeletal muscle hypertrophy, with protein intake saturating around 1.6 g/kg/day for general populations and potentially requiring 2.0-2.2 g/kg/day for resistance-trained individuals.Strong
- Trans fats should be completely eliminated from the diet, as they increase LDL cholesterol, decrease HDL cholesterol, and are directly associated with increased coronary risk.Strong
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