Adherence
Intensive lifestyle interventions (diet, exercise, or combined) fail to maintain long-term weight loss or behavioral changes beyond 6 months in overweight individuals with a family history of diabetes, resulting in no sustained difference in diabetes risk between treatment groups at 2 years.
Standard lifestyle interventions (diet and exercise programs) often fail to maintain weight loss or health benefits beyond 6 months for high-risk individuals. While initial weight loss is beneficial, the lack of long-term maintenance means that standard programs may not be sufficient for preventing diabetes over 2 years. More effective strategies to sustain engagement are needed.
After 6 months, there was gradual deterioration of behavioral and physiological changes, so that at 2 years, almost no between-group differences were maintained.
Why this rating
RCT design, but high attrition and poor adherence limit the generalizability of the 'failure' conclusion to other contexts.
Source
Lifestyle Intervention in Overweight Individuals With a Family History of Diabetes
Rena R. Wing et al. · Diabetes Care · 1998
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