Research

Adherence

Higher levels of objectively measured physical activity causally lower diastolic blood pressure and reduce the odds of hypertension.

To help lower your diastolic blood pressure, aim for higher levels of daily physical activity. This study provides strong causal evidence that moving more reduces hypertension risk. You do not need complex equipment; consistent, moderate movement is the key lever.

GoodSupportsHIGH confidence
Two-sample Mendelian randomisation suggests that increased activity might causally lower diastolic blood pressure (beta mmHg/SD: −0.91, SE = 0.18, p = 8.2 × 10−7), and odds of hypertension (Odds ratio/SD: 0.84, SE = 0.03, p = 4.9 × 10−8).
Aiden Doherty et al. · Nature Communications · 2018

Why this rating

Uses Mendelian Randomization with large sample sizes (91k discovery, 278k MR) and objective device-measured data, reducing self-report bias and confounding common in observational studies.

Source

GWAS identifies 14 loci for device-measured physical activity and sleep duration

Aiden Doherty et al. · Nature Communications · 2018

cohort · n=91105Cited 437×
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