Macro partitioning

Higher intake of trans-fatty acids (TFA) is associated with increased total mortality and cause-specific mortality (particularly cardiovascular and neurodegenerative diseases).

Avoid industrial trans fats, which are found in partially hydrogenated oils used in some fried foods and baked goods. Higher intake of trans fats is linked to a 13% higher risk of total mortality and a 20% higher risk of cardiovascular disease mortality. Check labels for 'partially hydrogenated oils' and minimize consumption.

StrongSupportsHIGH confidence

For TFA intake, a significant positive association with total mortality was observed (HR comparing extreme quintiles, 1.13; 95% CI, 1.07-1.18; P < .001 for trend)... TFA intake was associated with a 20% higher CVD mortality across quintiles (HR, 1.20; 95% CI, 1.08-1.33; P < .001 for trend).

Dong D. Wang et al. · JAMA Internal Medicine · 2016

Why this rating

Large prospective cohort studies with long follow-up and rigorous adjustment.

Source

Association of Specific Dietary Fats With Total and Cause-Specific Mortality

Dong D. Wang et al. · JAMA Internal Medicine · 2016

cohort · n=126233Cited 433×

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