Adherence
Intensive lifestyle intervention is cost-effective for preventing type 2 diabetes in high-risk adults over a 10-year horizon, yielding approximately $10,037 per QALY gained compared to placebo.
For high-risk individuals, committing to a structured lifestyle program involving 150 minutes of moderate exercise weekly and a 7% weight loss goal is a financially sound long-term investment. While the initial cost is higher than medication, the prevention of diabetes and associated medical costs makes it a valuable use of resources over 10 years.
When costs and outcomes were discounted at 3%, lifestyle cost $10,037 per QALY... Over 10 years, from a payer perspective, lifestyle was cost-effective and metformin was marginally cost-saving compared with placebo.
Why this rating
Large-scale, randomized controlled trial (DPP/DPPOS) with 10-year follow-up and intent-to-treat analysis.
Source
The 10-Year Cost-Effectiveness of Lifestyle Intervention or Metformin for Diabetes Prevention
The Diabetes Prevention Program Research Group · Diabetes Care · 2012
DOI 10.2337/dc11-1468
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