Hormonal
In type 2 diabetes, the presence of fatty liver is strongly correlated with visceral adipose tissue (VAT) and is associated with significantly higher insulin resistance, elevated plasma free fatty acids, and more severe dyslipidemia compared to diabetic patients without fatty liver.
If you have type 2 diabetes, getting a fatty liver is common and strongly linked to visceral fat and insulin resistance. It is not just about overall weight but specifically where fat is stored (visceral) and in the liver/muscle. This condition worsens insulin resistance and lipid profiles, so managing visceral adiposity is key to mitigating these risks.
Fatty liver was most strongly correlated with VAT (r = -0.57, P < 0.0001)... Volunteers with type 2 DM and fatty liver were substantially more insulin resistant than those with type 2 DM but without fatty liver (P < 0.001) and had higher levels of plasma free fatty acids (P < 0.01) and more severe dyslipidemia (P < 0.01).
Why this rating
Observational study with rigorous measurement (glucose clamp, CT imaging) but no intervention.
Source
Fatty liver in type 2 diabetes mellitus: relation to regional adiposity, fatty acids, and insulin resistance
David E. Kelley et al. · American Journal of Physiology-Endocrinology and Metabolism · 2003
DOI 10.1152/ajpendo.00117.2003
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