Research

Hormonal

In men, chronic insomnia combined with objectively measured short sleep duration (<6 hours) is associated with a significantly increased risk of all-cause mortality, independent of common comorbidities like hypertension and diabetes.

If you are a man with chronic insomnia and you objectively sleep less than 6 hours per night, your risk of death is significantly higher than men who sleep normally, even after accounting for high blood pressure, diabetes, and other factors. This risk is driven by physiological stress (HPA axis activation). You should seek objective sleep assessment (like a sleep study) rather than relying on how you feel, and prioritize treating the insomnia as a serious medical condition.

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In men, mortality risk was significantly increased in insomniacs who slept less than 6 hours compared to the 'normal sleep duration, no insomnia' group, (OR = 4.00, CI 1.14-13.99) after adjusting for diabetes, hypertension, and other confounders.
Alexandros N. Vgontzas et al. · SLEEP · 2010

Why this rating

Longitudinal, population-based study with objective polysomnographic data and adjustment for major confounders, though limited by sample size for subgroup analysis.

Source

Insomnia with Short Sleep Duration and Mortality: The Penn State Cohort

Alexandros N. Vgontzas et al. · SLEEP · 2010

DOI 10.1093/sleep/33.9.1159

cohort · n=1741Cited 419×
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DOI resolved against Crossref · corpus check 2026-06-10

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