Hormonal
Long-acting GLP-1 receptor agonists (dulaglutide, liraglutide, once-weekly exenatide) provide superior glycemic control (HbA1c and FPG reduction) compared to short-acting agents (EBID, lixisenatide) in type 2 diabetes patients.
If you have Type 2 Diabetes and need better blood sugar control, long-acting GLP-1 medications (like dulaglutide, liraglutide, or once-weekly exenatide) are more effective at lowering HbA1c and fasting glucose than short-acting versions (like twice-daily exenatide or lixisenatide). Choose a long-acting option for superior glycemic results, keeping in mind that all GLP-1s carry a risk of gastrointestinal side effects.
dulaglutide, liraglutide, and once-weekly exenatide are superior to EBID and lixisenatide at lowering HbA1c and FPG.
Why this rating
Based on a systematic review and mixed-treatment comparison meta-analysis of 34 RCTs involving 14,464 participants.
Source
Efficacy and safety of glucagon‐like peptide‐1 receptor agonists in type 2 diabetes: <scp>A</scp> systematic review and mixed‐treatment comparison analysis
Zin Zin Htike et al. · Diabetes Obesity and Metabolism · 2016
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