Research
Hormonal
Consumption of fructose-rich beverages (sugar-sweetened soda and orange juice) increases the risk of incident gout in women, whereas diet soda does not.
If you are a woman concerned about gout, limit your intake of sugar-sweetened sodas and orange juice. The risk increases significantly with 1-2+ servings per day. Diet sodas do not appear to carry this risk. Focus on reducing fructose-rich beverages rather than just purine-rich foods.
GoodSupportsHIGH confidence
Increasing intake of sugar-sweetened soda was independently associated with increasing risk of gout... The corresponding relative risks for orange juice were 1.41... and 2.42... Diet soft drinks were not associated with the risk of gout.
Why this rating
Large prospective cohort (N=78,906), long follow-up (22 years), validated dietary assessment, and confirmed incident cases, though observational design limits causal inference.
Source
Fructose-Rich Beverages and Risk of Gout in Women
Hyon K. Choi et al. · JAMA · 2010
DOI 10.1001/jama.2010.1638
cohort · n=78906Cited 315×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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