Research
Macro partitioning
In patients with established cardiovascular disease (secondary prevention), a Mediterranean-style diet reduces CVD mortality and total mortality compared to usual care.
If you have heart disease, following a Mediterranean diet supplemented with canola margarine can significantly reduce your risk of dying from heart disease or other causes. This is a critical step for long-term survival.
LimitedSupportsLOW confidence
Lyon Diet Heart Study... there was low-quality evidence of a reduction in adjusted estimates for CVD mortality (HR 0.35, 95% CI 0.15 to 0.82) and total mortality (HR 0.44, 95% CI 0.21 to 0.92)
Why this rating
Low quality evidence due to small number of trials (2 trials, 605 participants).
Source
Mediterranean-style diet for the primary and secondary prevention of cardiovascular disease
Karen Rees et al. · Cochrane Database of Systematic Reviews · 2019
DOI 10.1002/14651858.cd009825.pub3
Meta-analysis · 30 studiesCited 391×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
More from this paper
- Adherence to a Mediterranean-style diet significantly reduces systolic and diastolic blood pressure in adults without established cardiovascular disease (primary prevention).Moderate
- A Mediterranean-style diet reduces the risk of stroke in high-risk individuals, but does not significantly reduce total mortality or myocardial infarction compared to a low-fat diet.Moderate
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