Hormonal
High consumption of fish (more than three times per week) is associated with a significantly reduced risk of metastatic prostate cancer, whereas fish oil supplements show no such protective association.
To potentially lower your risk of developing aggressive, metastatic prostate cancer, aim to eat fish more than three times a week. Focus on fish like salmon, mackerel, sardines, bluefish, and swordfish, as well as canned tuna. Simply taking fish oil supplements does not appear to offer the same protection, suggesting the whole food is key. Note that other seafood like shrimp and lobster did not show this specific benefit.
Eating fish more than three times per week was associated with a reduced risk of prostate cancer, and the strongest association was for metastatic cancer (multivariate relative risk, 0.56; 95% confidence interval, 0.37– 0.86, compared with infrequent consumption, i.e., less than twice per month)... However, use of fish oil supplements, as compared with no use, was not associated with a decreased risk of prostate cancer.
Why this rating
Large prospective cohort (n=47,882), long follow-up (12 years), validated dietary assessment, and adjustment for multiple confounders including PSA testing propensity.
Source
A prospective study of intake of fish and marine fatty acids and prostate cancer.
Katarina Augustsson et al. · PubMed · 2003
Related findings · Hormonal
- Initial treatment for type 2 diabetes should be a combination of metformin and either an SGLT-2 inhibitor or a GLP-1 receptor agonist to achieve cardiorenal protection, rather than monotherapy or older agents like sulfonylureas.Strong
- For patients with specific monogenic obesity syndromes (leptin deficiency, POMC/PCSK1/LEPR mutations), targeted pharmacotherapy (recombinant leptin or setmelanotide) is highly effective and should be prioritized, unlike in polygenic obesity.Strong
- Continued weekly administration of 2.4 mg subcutaneous semaglutide prevents weight regain and promotes further weight loss in adults with overweight or obesity, whereas switching to placebo results in significant weight regain.Strong
This is one finding among thousands. Every one is graded and traced to its source, so you can see what the evidence actually supports. Browse the research →