Hormonal

GH therapy increases lean body mass and decreases body fat in both childhood-onset (CO) and adult-onset (AO) GH-deficient patients, but AO patients show greater improvements in lipid profiles (Total and LDL cholesterol reduction) and waist/hip ratio reduction compared to CO patients.

GH therapy will likely improve your muscle mass and reduce body fat regardless of when your deficiency started. However, if your deficiency started in childhood, you may not see the same improvements in your cholesterol levels or waist size as someone who developed the deficiency as an adult. This is because the metabolic regulation of lipids and fat distribution differs between those who grew up with the deficiency and those who acquired it later in life.