Research
Hormonal
Rapid increases in training load can cause immunosuppression, increasing illness risk if the athlete does not return to baseline within 7-21 days.
After a period of intense training, allow yourself 7-21 days to recover. If you don't feel back to baseline, you are at higher risk of illness. Monitor your health closely during this window.
GoodSupportsHIGH confidence
Immunosuppression occurs following a rapid increase in training load. Athletes who do not return to baseline levels within the latency period (7–21 days) are at higher risk of illness during this period.
Why this rating
Supported by the systematic review's findings on illness.
Source
Training Load and Fatigue Marker Associations with Injury and Illness: A Systematic Review of Longitudinal Studies
Christopher M. Jones et al. · Sports Medicine · 2016
DOI 10.1007/s40279-016-0619-5
systematic_reviewCited 380×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
More from this paper
- Rapid increases in training load (load intensification) and periods of accumulated high training load significantly increase the risk of injury and illness in athletes.Good
- Individual characteristics such as fitness, body composition, injury history, and age significantly impact internal training loads and susceptibility to injury/illness.Good
Related findings · Hormonal
- Initial treatment for type 2 diabetes should be a combination of metformin and either an SGLT-2 inhibitor or a GLP-1 receptor agonist to achieve cardiorenal protection, rather than monotherapy or older agents like sulfonylureas.Strong
- For patients with specific monogenic obesity syndromes (leptin deficiency, POMC/PCSK1/LEPR mutations), targeted pharmacotherapy (recombinant leptin or setmelanotide) is highly effective and should be prioritized, unlike in polygenic obesity.Strong
- Continued weekly administration of 2.4 mg subcutaneous semaglutide prevents weight regain and promotes further weight loss in adults with overweight or obesity, whereas switching to placebo results in significant weight regain.Strong
This is one finding among thousands. Every one is graded and traced to its source, so you can see what the evidence actually supports. Browse the research →