Adherence
Lifestyle interventions (dietary modification, weight loss, and exercise) significantly reduce the incidence of type 2 diabetes in overweight adults with impaired glucose tolerance, effectively mitigating genetic risk.
If you are overweight and have impaired glucose tolerance, committing to lifestyle changes (diet, exercise, weight loss) can cut your risk of developing type 2 diabetes by more than half. This is true even if you have a strong family history of the disease, as lifestyle changes can neutralize genetic risks.
Two large randomized cohorts of lifestyle interventions (dietary modification, weight loss, and exercise) in overweight adults (mean BMI 31 kg/m2) with impaired glucose tolerance achieved 58% reduction in the incidence of diabetes.
Why this rating
Based on large randomized cohorts and the Diabetes Prevention Program (DPP), which are high-quality clinical trials.
Source
Genetic and environmental factors associated with type 2 diabetes and diabetic vascular complications
Mariana Murea et al. · The Review of Diabetic Studies · 2012
DOI 10.1900/rds.2012.9.6
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