Macro partitioning

Carriers of the BMI-increasing FTO rs9939609 minor allele exhibit a specific genetic predisposition to consume higher dietary protein, independent of total energy intake or BMI.

If you carry the FTO risk variant for obesity, you may have a biological tendency to prefer protein-rich foods. Instead of viewing this as a flaw, use it: structure your meals to be higher in protein. This aligns with your genetic appetite signals, potentially making it easier to manage satiety and body weight without strictly counting total calories.