Hormonal
Ingestion of 20g whey protein isolate stimulates myofibrillar protein synthesis (MPS) significantly more than 20g micellar casein in elderly men, both at rest and after resistance exercise.
For older adults looking to build or maintain muscle, choosing whey protein over casein after exercise or meals may provide a stronger signal for muscle growth. A 20g dose of whey protein isolate was shown to stimulate muscle protein synthesis significantly more than the same amount of casein. This is likely due to whey's faster digestion and higher leucine content, which creates a sharper spike in amino acids in the blood.
We conclude that ingestion of isolated whey protein supports greater rates of MPS than micellar casein both at rest and after resistance exercise in healthy elderly men.
Why this rating
Randomized controlled trial with healthy elderly men, though small sample size (n=14).
Source
Greater stimulation of myofibrillar protein synthesis with ingestion of whey protein isolate <i>v.</i> micellar casein at rest and after resistance exercise in elderly men
Nicholas A. Burd et al. · British Journal Of Nutrition · 2012
DOI 10.1017/s0007114511006271
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