Adherence
Lifestyle modification (LSM) interventions significantly reduce diabetes incidence in adults at risk, and unlike medications, these effects are sustained for several years after the active intervention ends, although the magnitude of benefit declines over time.
Adopting combined diet and physical activity changes is the most effective long-term strategy for preventing diabetes in at-risk adults. While the protective effect diminishes slightly over many years, it remains significant (28% risk reduction) long after active counseling ends. To maximize longevity, focus on sustainable habits rather than short-term intensity, as the physiological benefits of weight loss and improved insulin sensitivity persist.
LSM interventions were sustained for several years; however, their effects declined with time, suggesting that interventions to preserve effects are needed.
Why this rating
Based on a meta-analysis of 43 randomized clinical trials involving 49,029 participants.
Source
Long-term Sustainability of Diabetes Prevention Approaches
J. Sonya Haw et al. · JAMA Internal Medicine · 2017
DOI 10.1001/jamainternmed.2017.6040
Related findings · Adherence
- Regular physical activity (at least 150 minutes/week of moderate-intensity) reduces all-cause and cardiovascular mortality by 20-30% and lowers the risk of type 2 diabetes by 25-35%.Strong
- Increasing physical activity from a sedentary lifestyle to an active one in middle adulthood significantly reduces the risk of coronary events compared to remaining sedentary.Strong
- Resistance exercise is the only intervention capable of consistently restoring muscle function and strength in sarcopenia, partially overcoming age-related anabolic resistance.Strong
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