Adherence

Trait sleep reactivity is a significant independent risk factor for the development of depression, mediated by the onset of insomnia.

Addressing sleep reactivity and preventing insomnia may be a critical strategy for reducing the risk of developing depression, especially in those prone to stress-induced sleep disruption.

GoodSupportsHIGH confidence

Trait sleep reactivity also constituted a significant risk for depression (OR = 1.67; P < 0.01) two years later (Time 3). Insomnia at Time 2 significantly mediated this effect (P < 0.05).

Christopher L. Drake et al. · SLEEP · 2014

Why this rating

Longitudinal design with 2-year follow-up for depression, controlling for baseline depression, age, and gender.

Source

Stress and Sleep Reactivity: A Prospective Investigation of the Stress-Diathesis Model of Insomnia

Christopher L. Drake et al. · SLEEP · 2014

cohort · n=2316Cited 343×

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