Hormonal
Administration of probiotics and prebiotics ameliorates metabolic disorders, including type 2 diabetes (T2DM) and cardiovascular disease (CVD), by modulating gut microbiota composition to stimulate insulin signaling and lower cholesterol.
To potentially improve metabolic health, consider incorporating probiotic and prebiotic sources into your diet. The paper suggests that fermented foods (like yogurt with specific bacteria) may be more effective than freeze-dried capsules because they are metabolically active upon ingestion. Look for products containing strains like Lactobacillus and Bifidobacterium, and prebiotics like inulin or fructooligosaccharides, as these have been linked to improved insulin sensitivity and lower cholesterol in studies.
Probiotics and prebiotics can ameliorate T2DM and CVD through improvement of gut microbiota, which in turn leads to insulin-signaling stimulation and cholesterol-lowering effects.
Why this rating
The paper is a review citing multiple human and animal studies, but notes conflicting results and the need for further research.
Source
Probiotics and Prebiotics: Present Status and Future Perspectives on Metabolic Disorders
Ji Youn Yoo et al. · Nutrients · 2016
DOI 10.3390/nu8030173
More from this paper
- Short-chain fatty acids (SCFAs) produced by gut microbiota fermentation activate G-protein coupled receptors (FFAR2/FFAR3), leading to increased secretion of GLP-1 and PYY, which improves insulin secretion and energy expenditure.Good
- Certain probiotic strains (e.g., Lactobacillus plantarum PH04, Bifidobacterium Bb-12) significantly reduce total cholesterol, LDL-cholesterol, and triglycerides in hypercholesterolemic individuals.Moderate
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