Research
Hormonal
Metformin is a common pharmacological insulin sensitization therapy used to treat PCOS, though specific dosing protocols are not detailed in this review excerpt.
Metformin is a standard medication for treating insulin resistance in PCOS. Consult a doctor for appropriate dosing and monitoring.
ModerateSupportsMEDIUM confidence
Common pharmacological approaches for reducing IR in women with PCOS are outlined in the chart below (Table 1). Metformin, the most
Why this rating
The paper mentions it as a common approach but cuts off before detailing specific protocols or efficacy data in this excerpt.
Source
Insulin resistance in polycystic ovary syndrome across various tissues: an updated review of pathogenesis, evaluation, and treatment
Han Zhao et al. · Journal of Ovarian Research · 2023
DOI 10.1186/s13048-022-01091-0
narrative_reviewCited 337×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
More from this paper
- Insulin resistance (IR) is a major driver of PCOS pathophysiology, present in 65-95% of women with PCOS, and is independent of and exacerbated by obesity.Strong
- Lifestyle interventions, specifically calorie-restricted diets combined with at least 150 minutes of weekly aerobic exercise, are the first-line treatment for improving insulin sensitivity in women with PCOS.Good
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