Macro partitioning
Higher consumption of dietary cholesterol (specifically >300 mg/day) is significantly associated with a higher risk of incident cardiovascular disease and all-cause mortality in a dose-response manner among US adults.
If you are concerned about heart disease, limiting dietary cholesterol to under 300 mg per day and moderating egg intake (less than half an egg per day) is associated with a lower risk of cardiovascular events and death. This is particularly important if you have existing risk factors like high blood pressure or diabetes.
Among US adults, higher consumption of dietary cholesterol or eggs was significantly associated with higher risk of incident CVD and all-cause mortality in a dose-response manner.
Why this rating
Large pooled prospective cohort study (N=29,615) with long follow-up (median 17.5 years) and rigorous adjustment for confounders, though observational design limits causal inference.
Source
Associations of Dietary Cholesterol or Egg Consumption With Incident Cardiovascular Disease and Mortality
Victor W. Zhong et al. · JAMA · 2019
DOI 10.1001/jama.2019.1572
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