Research
Hormonal
Genetic variants associated with restless legs syndrome (RLS) also influence sleep duration, quality, and timing.
If you have RLS, addressing it may improve overall sleep metrics.
GoodSupportsHIGH confidence
We observed most variants to be associated with either sleep quality, duration, or timing, but not combinations of these sleep characteristics. However, the variant rs113851554 at the MEIS1 locus was associated with sleep quality (sleep efficiency), duration, and timing (L5).
Why this rating
Mendelian Randomization supports causality.
Source
Genetic studies of accelerometer-based sleep measures yield new insights into human sleep behaviour
Samuel E. Jones et al. · Nature Communications · 2019
DOI 10.1038/s41467-019-09576-1
cohort · n=85670Cited 328×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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