Research
Hormonal
Physical activity stimulates the production and release of adiponectin, which enhances glucose uptake and fatty acid oxidation through AMPK activation.
Engage in regular physical activity to naturally boost your adiponectin levels. This hormone helps your muscles take up glucose and burn fat more efficiently. You do not need extreme workouts; consistent activity can reverse the low adiponectin levels associated with sedentary living.
GoodSupportsHIGH confidence
Practicing physical activity can revert such a condition, in that it stimulates the production and release of adiponectin, which enhances glucose uptake and fatty acids oxidation through 5’-adenosine monophosphate (AMP) kinase (AMPK) activation
Why this rating
Review paper citing multiple studies on exercise and adiponectin.
Source
Adiponectin: Structure, Physiological Functions, Role in Diseases, and Effects of Nutrition
Kayvan Khoramipour et al. · Nutrients · 2021
DOI 10.3390/nu13041180
narrative_reviewCited 317×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
More from this paper
- Adiponectin levels are negatively correlated with obesity, type 2 diabetes, and cardiovascular disease, and healthy nutrition (specifically unsaturated fats and omega-3) significantly increases adiponectin levels.Good
- Omega-3 fatty acid supplementation and consumption increase adiponectin levels, particularly in individuals with low basal levels, improving metabolic and oxidative profiles.Good
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