Hormonal
Moderate alcohol consumption increases HDL cholesterol levels by increasing the transport rate of apolipoproteins A-I and A-II, rather than by altering their fractional catabolic rate.
If you drink alcohol moderately, it may raise your HDL cholesterol levels by speeding up the production and transport of key proteins (apoA-I and apoA-II). This effect is dose-dependent, meaning more alcohol leads to a greater increase, up to a point. However, this does not necessarily mean heavy drinking is beneficial, as other health risks exist.
Alcohol intake increases HDL-C in a dose-dependent fashion, associated with and possibly caused by an increase in the TR of HDL apolipoproteins apoA-I and -II.
Why this rating
Randomized crossover trial with rigorous metabolic ward controls, though sample size is small (n=14).
Source
Alcohol Consumption Raises HDL Cholesterol Levels by Increasing the Transport Rate of Apolipoproteins A-I and A-II
Elizabeth R. De Oliveira e Silva et al. · Circulation · 2000
DOI 10.1161/01.cir.102.19.2347
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