Hormonal
Six weeks of CPAP therapy significantly reduces waking systolic and diastolic blood pressure and improves baroreceptor sensitivity in obese males with OSA, but does not alter insulin resistance, lipid profiles, or metabolic syndrome status within this timeframe.
If you are obese and have OSA, using CPAP nightly for at least 6 weeks will significantly lower your blood pressure and improve your heart's stress response. However, do not expect CPAP alone to fix your blood sugar, cholesterol, or weight in that short time; you must combine it with weight management strategies to address metabolic health.
Mean waking systolic and diastolic blood pressure fell by 6.7 and 4.9 mmHg, respectively, when compared with sham CPAP. No change was observed in glucose, lipids, insulin resistance or the proportion of patients with metabolic syndrome.
Why this rating
Randomized, placebo-controlled, blinded crossover trial with rigorous methodology, though limited by short duration (6 weeks) and specific population (obese, non-diabetic).
Source
Cardiovascular and metabolic effects of CPAP in obese males with OSA
Steven Coughlin et al. · European Respiratory Journal · 2007
DOI 10.1183/09031936.00043306
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