Adherence

Physical activity is inversely associated with insulin resistance and circulating metabolite levels, but these associations are largely attenuated when adjusting for HOMA-IR, suggesting physical activity improves insulin sensitivity directly rather than by lowering specific metabolite levels.

Exercise improves insulin sensitivity directly. While your blood tests might show changes in amino acids after exercising, these changes are likely just a reflection of your improved metabolic health, not the primary mechanism. Don't worry if your amino acid levels don't drop perfectly; focus on the consistency of your physical activity.