Hormonal
Acute total sleep deprivation enhances brain activation in the anterior cingulate cortex in response to hedonic food stimuli, increasing subjective appetite ratings independent of fasting plasma glucose levels.
If you are sleep-deprived, your brain's reward system becomes hypersensitive to food cues, specifically activating the anterior cingulate cortex. This happens regardless of your actual blood sugar levels. To mitigate this, prioritize getting adequate sleep, as acute sleep loss directly amplifies the neural drive to consume food.
Compared with sleep, total sleep deprivation was associated with an increased activation in the right anterior cingulate cortex in response to food images, independent of calorie content and prescan hunger ratings.
Why this rating
Randomized crossover design with fMRI, but small sample size (n=12) and specific population (healthy young men).
Source
Acute Sleep Deprivation Enhances the Brain's Response to Hedonic Food Stimuli: An fMRI Study
Christian Benedict et al. · The Journal of Clinical Endocrinology & Metabolism · 2012
DOI 10.1210/jc.2011-2759
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