Hormonal
Anti-obesity medications (AOMs) including orlistat, naltrexone/bupropion, phentermine/topiramate, liraglutide, and semaglutide are effective for long-term weight management in adults with BMI ≥ 25 kg/m² who have failed non-pharmacological treatments.
If you have obesity and lifestyle changes haven't worked, talk to your doctor about FDA-approved anti-obesity medications. Drugs like semaglutide (once-weekly injection or daily pill) and liraglutide (daily injection) can help you lose significant weight. Start with a low dose to minimize stomach upset, and work with your provider to find the right medication for your specific health needs.
In Korea, the Korean Society for the Study of Obesity strongly advocates for the use of pharmacotherapy in Korean adults with a body mass index of 25 kg/m² or higher who have not achieved weight reduction through non-pharmacological treatments. Currently, five AOMs have been approved for long-term weight management: orlistat, naltrexone/bupropion, phentermine/topiramate, liraglutide, and semaglutide.
Why this rating
Based on large-scale, randomized, double-blind, placebo-controlled trials (e.g., STEP, SCALE, SURMOUNT).
Source
Approved Anti-Obesity Medications in 2022 KSSO Guidelines and the Promise of Phase 3 Clinical Trials: Anti-Obesity Drugs in the Sky and on the Horizon
Eon Ju Jeon et al. · Journal of Obesity & Metabolic Syndrome · 2023
This is one finding among thousands. Every one is graded and traced to its source, so you can see what the evidence actually supports. Browse the research →