Research
Hormonal
Circadian misalignment from shift work or forced desynchronization causes insulin resistance and impaired glucose tolerance, independent of total sleep time.
If you work shifts, try to eat during your 'day' (even if it's night) and sleep during your 'night' (even if it's day). Aligning food intake with your internal clock reduces insulin resistance.
GoodSupportsHIGH confidence
healthy human volunteers subjected to circadian misalignment exhibited decreased insulin sensitivity, impaired compensatory insulin secretion and increased CRP (C-reactive protein) despite preserved total sleep time [211]. ... plasma glucose and insulin responses to a test meal were significantly higher when identical food was administered during the night as opposed to during the day [212].
Why this rating
Supported by experimental studies on forced desynchronization and observational studies on shift workers.
Source
The impact of sleep disorders on glucose metabolism: endocrine and molecular mechanisms
Anne Briançon‐Marjollet et al. · Diabetology & Metabolic Syndrome · 2015
DOI 10.1186/s13098-015-0018-3
narrative_reviewCited 304×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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