Hormonal
Faecal microbiota transplantation (FMT) using autologous stool preserves stimulated C-peptide levels (residual beta-cell function) in patients with new-onset type 1 diabetes over 12 months, whereas allogenic (healthy donor) FMT does not.
For individuals with very recent-onset Type 1 Diabetes, using their own gut bacteria (autologous FMT) may help preserve remaining insulin production, whereas using healthy donor bacteria does not offer this benefit. This is a specialized medical intervention, not a DIY protocol.
Stimulated C peptide levels were significantly preserved in the autologous FMT group (n=10 subjects) compared with healthy donor FMT group (n=10 subjects) at 12 months.
Why this rating
Randomized controlled trial, but terminated early due to funding (n=20), limiting statistical power and generalizability.
Source
Faecal microbiota transplantation halts progression of human new-onset type 1 diabetes in a randomised controlled trial
Pieter F. de Groot et al. · Gut · 2020
DOI 10.1136/gutjnl-2020-322630
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