Research

Macro partitioning

Replacing saturated and trans fatty acids with unsaturated fatty acids lowers LDL cholesterol and reduces cardiovascular disease risk, whereas simply reducing total fat without this substitution may worsen the lipid triad (high triglycerides, low HDL, small LDL particles).

Focus on swapping saturated fats (like butter or fatty meats) for unsaturated fats (like olive oil, nuts, or fish) rather than just cutting total fat. Simply eating less fat but replacing it with refined carbohydrates may not improve your cholesterol profile and could worsen it.

GoodQualifiesHIGH confidence
A diet that is low in saturated fatty acids, trans fatty acids, and cholesterol and relatively high in unsaturated fatty acids gives the best lipoprotein pattern. It keeps the LDL-cholesterol relatively low, and at the same time, it mitigates the lipid triad.
Alice H. Lichtenstein et al. · Nutrition Reviews · 2009

Why this rating

Supported by multiple epidemiologic studies (Nurses' Health Study) and clinical trials, though observational data has limitations.

Source

Dietary Fat Consumption and Health

Alice H. Lichtenstein et al. · Nutrition Reviews · 2009

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