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Resistance exercise intensity affects myofibrillar protein synthesis (MPS) in a dose-dependent manner at low intensities, plateauing between 60-90% of 1RM, while training status alters the specific protein fractions synthesized (myofibrillar vs. mitochondrial).

For muscle growth, you do not need to lift at maximum capacity. Research indicates that myofibrillar protein synthesis plateaus between 60% and 90% of your one-repetition maximum. Focus on this moderate-to-high intensity range for efficient hypertrophy.

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Our results indicate that the magnitude of the myofibrillar protein synthesis response is intensity dependent at low intensities, with a plateau at intensities between 60 and 90% of 1 RM.
Vinod Kumar et al. · Journal of Applied Physiology · 2009

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Based on specific human studies cited in the review.

Source

Human muscle protein synthesis and breakdown during and after exercise

Vinod Kumar et al. · Journal of Applied Physiology · 2009

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