Research

Hormonal

Obesity significantly increases the risk of cardiovascular diseases (CVDs), including hypertension, coronary artery disease, heart failure, and arrhythmias, through mechanisms involving inflammation, endothelial dysfunction, and cardiac structural changes.

If you have obesity, you are at a significantly higher risk for heart disease, high blood pressure, and heart failure. This risk is driven by inflammation and structural changes in the heart. Weight loss through lifestyle changes is crucial for managing these risks. Regular screening for blood pressure, cholesterol, and heart function is recommended.

StrongSupportsHIGH confidence
Obesity directly fosters the onset of various cardiovascular risk factors, such as dyslipidemia, T2DM, hypertension, and sleep disorders... obesity increases the risk of CVDs. Notably, obesity correlates with an increased occurrence of hypertension, coronary artery disease, heart failure, and arrhythmia.
Ning Xiao et al. · The Innovation Medicine · 2024

Why this rating

Supported by multiple prospective cohort studies, meta-analyses, and registry data cited in the review.

Source

Navigating obesity: A comprehensive review of epidemiology, pathophysiology, complications and management strategies

Ning Xiao et al. · The Innovation Medicine · 2024

narrative_reviewCited 30×
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