Hormonal
Regular physical exercise is the most effective non-pharmacological intervention for preventing and treating age-associated skeletal muscle changes (sarcopenia) by modulating anabolic/catabolic pathways and reducing oxidative stress.
To combat age-related muscle loss, engage in regular exercise combining aerobic activity (50-80% of your max heart rate, 2-3 times a week) and resistance training (50-80% of your one-rep max, 2 days a week). This approach is the most effective way to maintain muscle mass, strength, and functional capacity in older age.
Exercise is the most effective intervention in preventing and treating skeletal muscle changes and sarcopenia in older individuals. Exercise training not only attenuates muscle loss but increases muscle mass and strength, and improves functional capacity and survival.
Why this rating
The paper is a review summarizing various studies; it cites clinical trials but does not present a single primary trial itself.
Source
Skeletal muscle aging: influence of oxidative stress and physical exercise
Mariana Janini Gomes et al. · Oncotarget · 2017
DOI 10.18632/oncotarget.14670
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