Research
Adherence
Physical exercise improves insulin sensitivity and glucose disposal in skeletal muscle, partly through AMPK activation.
Regular moderate-intensity exercise combined with a healthy diet is the most effective way to prevent type 2 diabetes in high-risk individuals.
StrongSupportsVERY_HIGH confidence
Regular physical activity leads to a number of beneficial physiological changes that favourably affect muscle and liver insulin sensitivity, muscle glucose uptake and utilization and overall glycemic control.
Why this rating
Supported by observational studies, clinical trials, and mechanistic studies.
Source
Targeting the AMPK pathway for the treatment of Type 2 diabetes
Benoı̂t Viollet · Frontiers in bioscience · 2009
DOI 10.2741/3460
narrative_reviewCited 278×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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