Adherence
Sedentary time exceeding 10 hours per day is associated with a statistically significant increase in cardiovascular disease risk, whereas intermediate levels of sedentary time (up to ~7.5 hours) show no apparent increased risk compared to low sedentary time.
If you sit for more than 10 hours a day, your cardiovascular risk increases significantly, even if you exercise. However, sitting for moderate amounts (up to ~7.5 hours) does not appear to carry this same elevated risk. Focus your efforts on reducing extreme sitting durations (>10h) rather than stressing over moderate sitting, as the risk is nonlinear and threshold-based.
In continuous analyses, a nonlinear association between sedentary time and incident CVD was found (P for nonlinearity < .001), with an increased risk observed for more than 10 hours of sedentary time per day (pooled HR, 1.08; 95% CI, 1.00-1.14). However, no apparent risk associated with intermediate levels of sedentary time (HR for 7.5 h/d, 1.02; 95% CI, 0.96-1.08) was found.
Why this rating
Large-scale meta-analysis of 9 prospective cohort studies with >700,000 participants and high-quality Newcastle-Ottawa scores (mean 8.7/9), though subject to residual confounding and self-report bias.
Source
Continuous Dose-Response Association Between Sedentary Time and Risk for Cardiovascular Disease
Ambarish Pandey et al. · JAMA Cardiology · 2016
DOI 10.1001/jamacardio.2016.1567
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