Research
Macro partitioning
Obese and post-obese individuals have a diminished capacity to increase fat oxidation in response to high-fat diets compared to lean individuals.
If you are obese or have been obese, your body may not adapt to high-fat diets by burning more fat. This makes it harder to manage weight on such diets compared to lean individuals.
GoodQualifiesHIGH confidence
The lean and obese women responded to the high-fat diet by increasing fat oxidation, whereas in the post-obese women the increase in fat oxidation in response to the high-fat diet was blunted.
Why this rating
Supported by multiple studies comparing lean, obese, and post-obese subjects.
Source
The role of high-fat diets and physical activity in the regulation of body weight
Patrick Schrauwen et al. · British Journal Of Nutrition · 2000
DOI 10.1017/s0007114500001720
narrative_reviewCited 272×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
More from this paper
- High-fat diets promote obesity primarily by increasing voluntary energy intake due to high energy density and palatability, and by failing to stimulate fat oxidation, leading to positive fat balance.Good
- High-intensity exercise can counteract the fattening effects of high-fat diets by lowering glycogen stores, which rapidly increases fat oxidation.Good
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