Research

Macro partitioning

Dietary intake of polyunsaturated fatty acids (PUFA) is positively associated with fasting adiponectin levels, while saturated fatty acid (SFA) intake is negatively associated, suggesting that dietary fat quality modulates adiponectin secretion.

To support higher adiponectin levels, NASH patients should focus on increasing their intake of polyunsaturated fatty acids (PUFA) and reducing saturated fatty acids (SFA). This shift in dietary fat quality, rather than just total fat reduction, is associated with higher fasting adiponectin levels.

GoodSupportsHIGH confidence
Fasting adiponectin correlated with... PUFA intake expressed as percent energy (r = 0.60; P = .001)... On multiple regression analysis... PUFA intake (r = 0.40; P = .041) independently predicted fasting adiponectin levels.
Giovanni Musso et al. · Hepatology · 2005

Why this rating

The association is statistically significant and independent of other factors, though it is observational.

Source

Adipokines in NASH: Postprandial Lipid Metabolism as a Link Between Adiponectin and Liver Disease *

Giovanni Musso et al. · Hepatology · 2005

cross_sectional · n=50Cited 266×
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