Hormonal
Mid-day time-restricted feeding (mTRF), defined as an 8-hour eating window between 11:00 and 20:00, does not significantly improve insulin sensitivity, fasting glucose, body mass, or inflammation compared to ad libitum eating in healthy non-obese adults.
If you prefer eating later in the day (e.g., 11 AM to 7 PM), be aware that this specific mid-day TRF window may not improve insulin sensitivity, reduce body weight, or lower inflammation compared to normal eating habits in healthy, non-obese individuals. If metabolic health is your goal, shifting your eating window to end earlier (by 3 PM) may be more effective.
The eTRF group showed a larger reduction in HOMA-IR... than either the mTRF group... There were no differences in the change in FPG between the mTRF... and control groups... there were no differences in the changes in body mass between the mTRF... and control groups
Why this rating
Same RCT as N1, high internal validity for the comparison.
Source
Randomized controlled trial for time-restricted eating in healthy volunteers without obesity
Zhibo Xie et al. · Nature Communications · 2022
DOI 10.1038/s41467-022-28662-5
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