Hormonal
Long-term daily consumption of heat-inactivated Lactobacillus gasseri CP2305 tablets significantly reduces anxiety and sleep disturbance in healthy young adults under chronic stress, while improving objective sleep metrics and modulating gut microbiota.
If you are under chronic stress, taking a daily supplement of heat-inactivated Lactobacillus gasseri CP2305 (specifically strain CP2305) for at least 24 weeks may help lower anxiety and improve sleep quality. Ensure you avoid other probiotic-rich foods or supplements during this period to isolate the effect.
Intake of the CP2305 tablet significantly reduced anxiety and sleep disturbance relative to placebo... CP2305 significantly shortened sleep latency and wake time after sleep onset and increased the delta power ratio in the first sleep cycle. CP2305 also significantly lowered salivary chromogranin A levels... attenuated the stress-induced decline of Bifidobacterium spp. and the stress-induced elevation of Streptococcus spp.
Why this rating
Randomized, double-blind, placebo-controlled trial with a reasonable sample size (n=60) and long duration (24 weeks), though limited to a specific demographic (Japanese medical students).
Source
Health Benefits of Lactobacillus gasseri CP2305 Tablets in Young Adults Exposed to Chronic Stress: A Randomized, Double-Blind, Placebo-Controlled Study
Kensei Nishida et al. · Nutrients · 2019
DOI 10.3390/nu11081859
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