Research
Hormonal
Low Vitamin D status (serum <50 nmol/L) is consistently associated with frailty, muscle weakness, and increased mortality risk in elderly populations.
Check your Vitamin D levels if you are elderly or frail. Low levels are linked to muscle weakness and higher mortality. Supplementation is recommended for those at risk of falls or frailty, independent of bone health.
GoodSupportsHIGH confidence
A low vitamin D status is consistently associated with the frail phenotype... Frail individuals with a low vitamin D level were at increased risk (hazard ratio of 2.98) of death during the follow-up compared to robust individuals with a high level of vitamin D.
Why this rating
Strong observational data and prospective studies cited.
Source
Vitamin D: A Review on Its Effects on Muscle Strength, the Risk of Fall, and Frailty
Matthieu Halfon et al. · BioMed Research International · 2015
DOI 10.1155/2015/953241
narrative_reviewCited 261×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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