Hormonal
GLP-1 receptor agonists (GLP-1RAs) provide high glycemic efficacy and facilitate weight loss in type 2 diabetes without conferring a risk of hypoglycemia.
GLP-1 receptor agonists are injectable medications that effectively lower blood sugar and help with weight loss in type 2 diabetes without causing low blood sugar. They come in daily or weekly formulations. Side effects like nausea are common initially but often improve over time. They are particularly useful for patients who need to avoid weight gain or hypoglycemia associated with other diabetes medications like insulin or sulfonylureas.
GLP-1 RAs have demonstrated a high level of glycemic efficacy, without conferring risk of hypoglycemia, while physiologically facilitating weight loss.
Why this rating
Based on a review of multiple phase 3 randomized controlled trials (RCTs).
Source
A review of GLP‐1 receptor agonists: Evolution and advancement, through the lens of randomised controlled trials
Vanita R. Aroda · Diabetes Obesity and Metabolism · 2018
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