Hormonal
The Triglyceride-Glucose (TyG) index provides accurate discrimination of prediabetes and diabetes, performing comparably to the gold-standard HOMA-IR marker, particularly in women and individuals under 65 years of age.
If you are concerned about prediabetes, ask your doctor to calculate your Triglyceride-Glucose (TyG) index using your standard fasting glucose and triglyceride levels. This index is a reliable, low-cost screening tool for insulin resistance and diabetes risk, especially for women and those under 65, potentially saving you the cost and discomfort of an oral glucose tolerance test.
In conclusion, TyG and LAP provide good discrimination of persons with prediabetes/diabetes... the accuracy of TyG was superior to VAI and LAP... TyG did not show inferior ability compared to the HOMA-IR.
Why this rating
Large cross-sectional study (n=2,045) with rigorous statistical validation (ROC, Youden Index) and sensitivity analyses.
Source
Visceral adiposity index (VAI), lipid accumulation product (LAP), and product of triglycerides and glucose (TyG) to discriminate prediabetes and diabetes
Nayeon Ahn et al. · Scientific Reports · 2019
DOI 10.1038/s41598-019-46187-8
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