Macro partitioning
Antecedent diet composition (specifically high-fat vs. high-carbohydrate) significantly modulates postprandial net de novo lipogenesis and thermogenesis following a large carbohydrate load, with high-fat adaptation suppressing lipogenesis and increasing glycogen storage.
If you eat a high-carb meal, your body's response depends on what you've been eating recently. If you've been eating high-fat, your body will store more of that carb as glycogen and make very little fat. If you've been eating high-carb, you'll synthesize slightly more fat, but the total amount is negligible and doesn't lead to net fat gain in a day. Don't fear carbs; focus on your overall diet pattern and glycogen needs.
CHO oxidation and conversion to fat was significantly less in the high-fat diet group (222 +/- 5 g) than in the mixed (300 +/- 13 g) or high-CHO diet (331 +/- 7 g) groups, resulting in a greater glycogen storage in the high-fat (278 +/- 6 g) than in the other two groups (197 +/- 11 and 170 +/- 2 g).
Why this rating
Controlled clinical trial with indirect calorimetry and precise substrate balance calculations in healthy young men.
Source
Nutritional influences on lipogenesis and thermogenesis after a carbohydrate meal
K. J. Acheson et al. · American Journal of Physiology-Endocrinology and Metabolism · 1984
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