Hormonal
Male obesity causes male subfertility through hormonal imbalance (hypogonadism), chronic inflammation, oxidative stress, and increased scrotal temperature, leading to reduced sperm quality and DNA damage.
If you are overweight or obese, your fertility may be compromised due to hormonal changes, inflammation, and heat stress on the testes. Losing weight through lifestyle changes or surgery can improve testosterone levels and sperm count, suggesting that weight management is a critical step for men trying to conceive.
Obesity, a serious etiologic factor for male subfertility in modern society... obesity is correlated with reductions in sperm concentration and motility, increase in sperm DNA damage and changes in reproductive hormones.
Why this rating
The paper is a review citing multiple clinical investigations and animal experiments, establishing strong correlation and plausible biological mechanisms.
Source
Obesity, a serious etiologic factor for male subfertility in modern society
Yue Liu et al. · Reproduction · 2017
DOI 10.1530/rep-17-0161
More from this paper
- Obesity-induced hypogonadism reduces testosterone and FSH levels, disrupting the blood-testis barrier and spermatogenesis.Good
- Obesity increases scrotal temperature due to increased scrotal adiposity, which reduces sperm motility and concentration and increases DNA damage.Good
- Obesity induces chronic inflammation and oxidative stress in the reproductive tract, damaging sperm DNA and membrane lipids.Good
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