Hormonal
Daily intake of Lactobacillus reuteri (2x10^10 cells) for 4 weeks increases glucose-stimulated GLP-1 and GLP-2 secretion, which in turn increases insulin and C-peptide secretion in glucose-tolerant humans.
Taking Lactobacillus reuteri (20 billion cells twice daily) for a month can boost your body's production of GLP-1 and GLP-2 hormones after meals, which helps your pancreas release more insulin. However, this does not make your body more sensitive to insulin or help you lose weight if you are already healthy. It is a specific hormonal boost, not a general metabolic fix.
daily administration of L. reuteri increased glucose-stimulated GLP-1 and GLP-2 release by 76% (P < 0.01) and 43% (P < 0.01), respectively, compared with placebo, along with 49% higher insulin (P < 0.05) and 55% higher C-peptide secretion (P < 0.05).
Why this rating
Randomized, double-blind, placebo-controlled trial with rigorous metabolic clamps, but small sample size (n=21) and short duration (4 weeks).
Source
Intake of <i>Lactobacillus reuteri</i> Improves Incretin and Insulin Secretion in Glucose-Tolerant Humans: A Proof of Concept
Marie‐Christine Simon et al. · Diabetes Care · 2015
DOI 10.2337/dc14-2690
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